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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WIPF1
All Species:
27.27
Human Site:
S137
Identified Species:
50
UniProt:
O43516
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43516
NP_001070737.1
503
51275
S137
P
P
G
G
R
S
T
S
A
K
P
F
S
P
P
Chimpanzee
Pan troglodytes
XP_001150374
510
51924
S137
P
P
G
G
R
S
T
S
A
K
P
F
S
P
P
Rhesus Macaque
Macaca mulatta
XP_001090880
510
52064
S137
P
P
G
G
R
S
T
S
A
K
P
F
S
P
P
Dog
Lupus familis
XP_545531
517
52682
S149
P
P
G
G
R
S
T
S
A
K
P
F
P
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1I7
493
50062
S138
P
P
G
G
R
A
T
S
A
K
P
F
S
P
P
Rat
Rattus norvegicus
Q6IN36
487
49732
S133
P
P
G
G
R
A
T
S
A
K
P
F
S
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515714
498
50998
S132
P
P
G
G
R
A
M
S
A
K
P
F
S
P
P
Chicken
Gallus gallus
NP_001012935
494
49866
A129
P
P
G
A
R
S
A
A
A
K
P
F
S
A
P
Frog
Xenopus laevis
NP_001079978
426
44520
G81
P
G
F
G
A
T
P
G
M
A
L
Q
P
K
G
Zebra Danio
Brachydanio rerio
XP_001919866
485
49016
G129
P
P
V
A
R
T
T
G
P
R
P
F
G
G
G
Tiger Blowfish
Takifugu rubipres
NP_001098701
410
41639
R65
P
R
G
R
P
N
V
R
Q
D
T
P
G
G
A
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195725
392
41038
G44
L
L
G
D
I
H
K
G
M
K
L
K
K
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37370
817
82575
S111
K
H
I
N
N
N
A
S
T
K
P
S
P
S
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
96.6
85.8
N.A.
88.6
87.4
N.A.
80.9
73.1
40.5
58.6
39.3
N.A.
N.A.
N.A.
35.9
Protein Similarity:
100
98.2
97.6
90.3
N.A.
92
91.6
N.A.
87.2
82.1
50.5
68.1
48.3
N.A.
N.A.
N.A.
42.5
P-Site Identity:
100
100
100
86.6
N.A.
93.3
86.6
N.A.
86.6
73.3
13.3
40
13.3
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
100
93.3
N.A.
93.3
80
20
53.3
20
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
8
24
16
8
62
8
0
0
0
8
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
70
0
0
0
% F
% Gly:
0
8
77
62
0
0
0
24
0
0
0
0
16
16
16
% G
% His:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
8
0
0
77
0
8
8
8
0
% K
% Leu:
8
8
0
0
0
0
0
0
0
0
16
0
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
16
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
16
0
0
0
0
0
0
0
0
0
% N
% Pro:
85
70
0
0
8
0
8
0
8
0
77
8
24
47
54
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% Q
% Arg:
0
8
0
8
70
0
0
8
0
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
39
0
62
0
0
0
8
54
16
0
% S
% Thr:
0
0
0
0
0
16
54
0
8
0
8
0
0
8
0
% T
% Val:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _